課程資訊
課程名稱
流行病學原理
Principles of Epidemiology 
開課學期
112-1 
授課對象
公共衛生學院  全球衛生碩士學位學程  
授課教師
張慶國 
課號
MGH7049 
課程識別碼
853EM0490 
班次
 
學分
2.0 
全/半年
半年 
必/選修
必修 
上課時間
星期四6,7(13:20~15:10) 
上課地點
公衛208 
備註
本課程以英語授課。全球衛生學程必修課,外系所學生欲選修者請先洽詢主授教師。
限本系所學生(含輔系、雙修生) 且 限公衛學院學生(含輔系、雙修生)
總人數上限:32人 
 
課程簡介影片
 
核心能力關聯
核心能力與課程規劃關聯圖
課程大綱
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課程概述

The aim of this course is to introduce basic concepts of epidemiology in study design, data collection, and preliminary analyses of health-related research with assignments and discussions involved. In the first part, the instructor will give an introduction of the roles played by epidemiology in public health and global health. In the second part, lectures about major ways of quantifying health events in the population and their usage of them for the estimation of relative risks will be given. The third part will be the considerations of causal inferences, identification and management of potential biases as the basis of fair comparisons in health-related studies. At last, the fourth part will cover the details of basic observational and intervention study designs. The assignments will be closely attached to the lectures previously given for a better understanding of the contents. Real-life examples from each aspect of global health research topics and related literature are given and illustrated in the course. 

課程目標
At the end of the course, students should have the following core knowledge and competencies:

1. To understand the principle of epidemiology and causal inference

2. To explain how random variation and bias affect public health research findings

3. To understand the principle of epidemiologic study design in experimental and observational studies

4. To critically appraise public health literature in terms of validity and applicability 
課程要求
The slides of each lecture and scientific papers for discussion will be made available on the course website for students to download before each class. 
預期每週課後學習時數
 
Office Hours
另約時間 備註: email: chinkuochang@ntu.edu.tw for making an appointment 
指定閱讀
 
參考書目
To de assigned in classes 
評量方式
(僅供參考)
   
針對學生困難提供學生調整方式
 
上課形式
以錄影輔助
作業繳交方式
考試形式
其他
由師生雙方議定
課程進度
週次
日期
單元主題
Week 1
9/7  Orientation

Introduction of Epidemiology in Global Health 
Week 2
9/14  Natural History of Disease

Dynamics of Disease Transmission 
Week 3
9/21  Measuring the Occurrence of Disease

Survey, Sampling, and Prototype of Epidemiologic Study Designs  
Week 4
9/28  Risk and Relative Risk (Assignment 1) 
Week 5
10/5  Causal Inferences, Bias, Confounding, and Interaction (Assignment 2) 
Week 6
10/12  Cohort Study 1: Principles 
Week 7
10/19  Cohort Study 2: Standardization & Lifetable (Assignment 3) 
Week 8
10/26  Midterm exam (20%) 
Week 9
11/2  Case-Control Study 1: Principles 
Week 10
11/9  Case-Control Study 2: Mantel-Haenszel methods & selection bias versus confounding (Assignment 4) 
Week 11
11/16  Special Topic: Causal Inference in Psychiatric Epidemiology: How to ask and answer a meaningful research question? (Speech given 12:30-13:20 at Room 505 by Dr. Chao-Yu Liu, MD, PhD) 
Week 12
11/23  Diagnosis, Tests, and Screening 
Week 13
11/30  Randomized Clinical Trial (RCT) 1: Philosophy and Practical Issues of RCTs (Assignment 5) 
Week 14
12/7  Randomized Clinical Trial (RCT) 2: Analysis and Interpretation & Discussion 
Week 15
12/14  Review for Final Exam 
Week 16
12/21  Final written exam (30%)

Review & Discussion